5-(2-Aminoethylamino)- 1-naphthalenesulfonic acid, sodium salt (1,5-EDANS, Na+salt)

Product ID: M0084

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Water soluble blue-green fluorescent labeling reagent for modification of proteins and carbohydrates.

The EDANS-DABCYL fluorophore-quencher pair is commonly used as a resonance energy transfer pair for peptidase substrate (FRET) analysis. See references below for more information. See also our Product M0273 for more information.

Technical Data
SKU M0084
CAS Number 100900-07-0
Unit Size 250mg
Absorption 336nm
Emission Wavelength 490
Extinction 6.2
Detection Method Fluorescence
Molecular Formula C₁₂H₁₃N₂O₃SNa
Molecular Weight 288.3
Soluble In H2O, DMSO
Storage Conditions Protect From Light, Desiccated

References and Citations


  • "A general method for the preparation of internally quenched fluorogenic protease substrates using solid-phase peptide synthesis." Maggiora LL, Smith CW, Zhang ZY. J. Med. Chem. 35: 3727-3730 (1992).
  • "Optical detection of cationic surfactants based on ion pairing with an environment-sensitive fluorophore." Shakhsher ZM, Seitz WR. Anal. Chem. 62(17): 1758-1762 (1990).
  • "Design and synthesis of new fluorogenic HIV protease substrates based on resonance energy transfer." Wang GT, Matayoshi E, Huffaker HJ, Krafft GA. Tetrahedron Lett. 31(45): 6493-6496 (1990).
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