3,5-Di-O-(p-toluyl)-2-deoxy-D-ribofuranosyl chloride

Product ID: M0189



Unit SizePriceQuantity 
1g
$467.57
  • Buy 5 for $374.06 each and save 21%

Availability: In stock


Description

Intermediate for deoxynucleotide synthesis. This reactive anomeric chloride derivative reacts with nucleophilic bases to provide β-D-ribofuranosyl glycosides.

This reactive ribose analog is a widely used synthon for DNA nucleoside analog preparations. This highly pure active sugar is useful for nucleotide analog syntheses, particularly if one is using a base analog and an unnatural nucleotide is required. Ask about bulk quantity availability.

Technical Data
SKU M0189
CAS Number 4330-21-6
Unit Size 1g
Molecular Formula C₂₁H₂₁ClO₅
Molecular Weight 388.83
Soluble In CHCl3
Storage Conditions -20C, Desiccated
Notes Purity: > 95% (alpha anomer)

References and Citations

References:

  • "Oligodeoxynucleotides containing synthetic abasic sites." Takeshita M, Chang CN, Johnson F, Will S, Grollman AP. J Biol. Chem. 262(21): 10171-10179 (1987).

  • Bhar CC. Synth. Proc. Nucl. Acid Chem. 1:521-522 (1968).

  • Hoffer M. Chem. Ber. 93: 2777 (1960).

>Show more
>Show less

Click here for Newsletter articles about this product


Technical Support

Question about this product? Ask a Scientist!

We pride ourselves on the high quality of our products and want you to get the best possible results from your assays. If you have any questions about this product or need help optimizing your protocol check out the product FAQs below or ask your own question and one of our expert scientists will get back to you asap:


There are currently no frequently asked questions for this product, click the button above to ask a question

Recently Viewed Products
  1. 3-Azido-7-hydroxycoumarin

    3-Azido-7-hydroxycoumarin

  2. BODIPY® FL Prazosin equivalent

    BODIPY® FL Prazosin equivalent

  3. NBD-X

    NBD-X