3-Dansylaminophenylboronic acid

Product ID: M0329

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Fluorescent labeling agent for cis-diols (sugars) at high pH values on cell surfaces and in vitro for carbohydrate determination in glycoproteins and for HPLC analysis of sugars.

3-Dansylaminophenylboronic acid can be used to label vicinal diols (hydroxyl groups on adjacent carbon atoms) of sugars, oligosaccharides and certain amino alcohols to form stable cyclic complexes that a have a fluorescence intensity and peak emission dependent on the environment of the dansyl fluorophore. The fluorescence emission of the dansyl fluorophore is sensitive. This compound is also known to be an active site inhibitor for lipases and certain serine proteases.

Technical Data
SKU M0329
CAS Number 75806-94-9
Unit Size 50mg
Alternative Names 3-(5-Dimethylamino-1-naphthalenesulfonyl)-3-aminobenzene boronic acid), m-Dansylaminophenylboronic acid
Absorption 337nm
Emission Wavelength 517
Detection Method Fluorescence
Molecular Formula C₁₈H₁₉O₄N₂BS
Molecular Weight 370.22
Storage Conditions 2-8C, Desiccated

References and Citations


  • "Selective Fluorescent Chemosensor for Fructose." Luis G.P., et al., Analyst 123: 155 (1998).

  • "Determination of Traces of Natural Brassinosteroids as Dansylaminophenylboronates by Liquid Chromatography with Fluorometric Detection." Gamoh K., et al., Anal. Chim. Acta 228: 101 (1990).

  • "Fluorometric Measurement of Glycosylated Albumin in Human Serum." Hayashi Y, Makino M., Clin. Chim. Acta 149: 13-19 (1985).

  • "N-(5-Dimethylaminonaphthalene-1-Sulfonyl)-3-Aminobenzene Boronic Acid as an Active-Site-Directed Fluorescent Probe of Lipoprotein Lipase." Vainio P., Biochim. Biophys. Acta 746: 217-219 (1983).

  • "Synthesis of a Fluorescent Boronic Acid Which Reversibly Binds to Cell Walls and a Diboronic Acid Which Agglutinates Erythrocytes." Burnett T.J., Peebles H.C., Hageman, J.H., Biochem. Biophys. Res. Commun. 96: 157-162 (1980).

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