4-Methylumbelliferyl sulfate, potassium salt

Product ID: M1388



Unit SizePriceQuantity 
25mg
$37.97
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Availability: In stock


Description

Highly sensitive fluorescent substrate for monitoring aryl sulfatase activity.

This substrate has been used in several methods for discovery of tyrosine sulfotransferase inhibitors, in particularly in P-selectin glycoprotein ligand-1 binding. The substrate is virtually non-fluorescent until cleavage by sulfatase enzymes, then emits blue fluorescence (450 nm) with excitation at 360 nm.

Technical Data
SKU M1388
CAS Number 15220-11-8
Unit Size 25mg
Alternative Names Potassium 4-methylumbelliferyl sulfate
Absorption 360nm
Emission Wavelength 450
Detection Method Fluorescence
Molecular Formula C₁₀H₇KO₆S;
Molecular Weight 294.32
Storage Conditions -20C, Desiccated

References and Citations

References:

  • Best MD, Brik A, Chapman E, Lee LV, Cheng WC, Wong CH (2004) "Rapid Discovery of Potent Sulfotransferase Inhibitors by Diversity-Oriented Reaction in Microplates Followed by in situ Screening" 5(6): 811 - 819.
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