Molecular Weight: 434.3

Storage: F,D,L

[C=Cold D=Desiccated F=Frozen L=Light Sensitive RT=Room Temperature]

Soluble: H₂O

Absorption: (in nm) 336

Emission: (in nm) 482

Extinction (10³): 5.7

Molecular Formula: C₁₄H₁₅IN₂O₄S

CAS Number: [36930-63-9]

Description:
A reactive version of the fluorophore 1,5-EDANS that can be used to label proteins or peptides (via free amino groups).

Application:
Blue-green fluorescent dye label

References:

• "Derivatization strategies for preparing N-glycan probes." Rice, KG. Anal. Biochem. 283: 10 (2000).
• "Adventures in membrane protein topology." Tory MC, Merrill AR. J Biol. Chem. 274(35): 24539-49 (1999).
• "Properties of spin and fluorescent labels at a receptor-ligand interface." Owenius R, Osterlund M, Lindgren M, Svensson M, Olsen OH, Persson E, Freskgard PO, Carlsson U. Biophys. J. 77(4): 2237-2250 (1999).
• "Intradomain distances in the regulatory domain of the myosin head in prepower and postpower stroke states: fluorescence energy transfer." Palm T, Sale K, Brown L, Li H, Hambly B, Fajer PG. Biochemistry 38(40): 13026-13034 (1999).
• "Conformational state of ovalbumin at acidic pH as evaluated by a novel approach utilizing intrachain sulfhydryl-mixed disulfide exchange reactions." Tatsumi E, Yoshimatsu D, Hirose M. Biochemistry 37: 12351 (1998).
• "Synthetic interface peptides as inactivators of multimeric enzymes: inhibitory and conformational properties of three fragments from Lactobacillus casei thymidylate synthase." Prasanna V, Bhattacharjya S, Balaram P. Biochemistry 37(19): 6883-6893 (1998).