
Molecular Weight: 388.83
Storage: F, D
[C=Cold D=Desiccated F=Frozen L=Light Sensitive RT=Room Temperature]
Soluble: CHCl3
Molecular Formula: C12H21ClO5
CAS Number: [4330-21-6]
Unit Price (USD):
1 g $361.75
Bulk Price/unit (when you buy 5 or more): $289.40
Description: Intermediate for deoxynucleotide synthesis. This reactive anomeric chloride derivative reacts with nucleophilic bases to provide β-D-ribofuranosyl glycosides.
Note: Purity: > 95% (alpha anomer)
Application: Widely used synthon for DNA nucleoside analog preparations. This highly pure active sugar is useful for nucleotide analog syntheses, particularly if one is using a base analog and an unnatural nucleotide is required. (High purity grade 99+%)
References:
"Oligodeoxynucleotides containing synthetic abasic sites." Takeshita M, Chang CN, Johnson F, Will S, Grollman AP. J Biol. Chem. 262(21): 10171-10179 (1987). Bhar CC. Synth. Proc. Nucl. Acid Chem. 1:521-522 (1968). Hoffer M. Chem. Ber. 93: 2777 (1960).
Keywords:
Deoxy-D-Ribofuranosyl Chloride, Deoxy, Deoxy-D-Ribofuranosyl, Chloride, Ribofuranosyl, Marker Gene
|