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CAS Number: 4330-21-6
Description: Intermediate for deoxynucleotide synthesis. This reactive anomeric chloride derivative reacts with nucleophilic bases to provide β-D-ribofuranosyl glycosides.
Application: Widely used synthon for DNA nucleoside analog preparations. This highly pure active sugar is useful for nucleotide analog syntheses, particularly if one is using a base analog and an unnatural nucleotide is required. (High purity grade 99+%) Note: Purity: > 95% (alpha anomer)
View Technical Information ▼
Molecular Weight: 388.83
Storage: F, D
[C=Cold D=Desiccated F=Frozen L=Light Sensitive RT=Room Temperature]
Soluble: CHCl3
Molecular Formula: C21H21ClO5
References: View References ▼
"Oligodeoxynucleotides containing synthetic abasic sites." Takeshita M, Chang CN, Johnson F, Will S, Grollman AP. J Biol. Chem. 262(21): 10171-10179 (1987). Bhar CC. Synth. Proc. Nucl. Acid Chem. 1:521-522 (1968). Hoffer M. Chem. Ber. 93: 2777 (1960).
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Unit Price (USD):
1 g $398.84
Bulk Price/unit (5 or more): $319.07
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