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CAS Number: 86701-10-2
Description:
NBD-ceramide analog used to detect, at the cellular level, a variety of lysosomal storage diseases as well as intracellular distribution and transport of the labeled sphingolipid molecules in living cells.
Application:
Ceramides are the biological building blocks of more complex sphingolipids. Metabolism of ceramides typically occurs in Golgi and endoplasmic reticulum membranes.
View Technical Information ▼
Molecular Weight: 575.75
Storage: F, D
[C=Cold D=Desiccated F=Frozen L=Light Sensitive RT=Room Temperature]
Absorption: (in nm) 460
Emission: (in nm) 534
Molecular Formula: C30H49N5O6
References:
View References ▼
- "Molecular cloning and functional analysis of apoxin I, a snake venom-derived apoptosis-inducing factor with L-amino acid oxidase activity." Torii S, Yamane K, Mashima T, Haga N, Yamamoto K, Fox JW, Naito M, Tsuruo T. Biochemistry 39(12): 3197-3205 (2000).
- "Selective accumulation of the endoplasmic reticulum-golgi intermediate compartment induced by the antitumor drug KRN5500." Kamishohara M, Kenney S, Domergue R, Vistica DT, Sausville EA. Exp. Cell Res. 256(2): 468-479 (2000).
- "Involvement of sphingosine in mitochondria-dependent Fas-induced apoptosis of type II jurkat T cells." Cuvillier O, Edsall L, Spiegel S. J Biol. Chem. 275: 15691 (2000).
- "Defining lipid transport pathways in animal cells." Pagano RE, Sleight RG. Science 229: 1051 (1985).
- "A vital stain for the golgi apparatus." Lipsky NG, Pagano RE. Science 228: 745 (1985).
- "Intracellular translocation of fluorescent sphingolipids in cultured fibroblasts: endogenously synthesized sphingomyelin and glucocerebroside analogues pass through the golgi apparatus en route to the plasma membrane." Lipsky NG, Pagano RE. J Cell Biol. 100: 27 (1985).
- "Intracellular processing of lipids: a theory based on studies with fluorescent lipids, liposomes, and cells." Pagano RE. Liposome Letters, A.D. Bangham, Ed., pp. 83-96 (1983).
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Unit Price (USD):
1 mg $154.35
Bulk Price/unit
(5 or more): $123.48
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