Molecular Weight: 540.46
Storage: F, D
[C=Cold D=Desiccated F=Frozen L=Light Sensitive RT=Room Temperature]
Molecular Formula: C27H24O12
CAS Number: [N/A]
Unit Price (USD):
10 mg $127.60
Bulk Price/unit (when you buy 5 or more): $102.08
Description:
Has been used in labeling of the interstitial (intercellular) spaces between neurons in vitro.
Note:
This structure presented is tentative. This product is sold as a mixture of 5- and 6- carboxyfluorescein mannitol esters, and there may be other isomers present, esterified to other hydroxyls of mannitol.
Application:
Since D-mannitol is preferentially excluded by neuronal cell membranes, this derivative of mannitol has been used to measure the fluid area between neurons.
References:
Haglund M. M., Hochman D. W., (2005), "Furosemide and mannitol suppression of epileptic activity in the human brain." Journal of neurophysiology 94(2): 907-18.
Hameed, B., Smith, D.M., Verrechio, J.J., Schmidt, J.D., Gillooley, L.E., Valenzano, M.C., Lewis, S.A., Mullin, J.M., "Indocyanine Green Alters Transepithelial Electrical Parameters of the Distal Colon." Digestive Diseases and Sciences (2004), 49(9), 1381-1386.
Keywords:
Monofluoresceinated Mannitol, MFM, Monofluoresceinated, Mannitol, carboxyfluorescein, Marker Gene
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