Molecular Weight: 266.31
Storage: L, D
Soluble: H2O (pH>eight) ; DMSO
Absorption: (in nm) 336
Emission: (in nm) 490
Extinction (103): 9.1
Molecular Formula: C12H14N2O3S
CAS Number: [50402-56-7]
Unit Price (USD):
10 mg $34.70
Bulk Price/unit (when you buy 5 or more): $27.76
Description:
EDANS is a bright fluorescent labeling reagent for modification of proteins and carbohydrates. The EDANS-DABCYL fluorophore-quencher pair is commonly used as a resonance energy transfer pair for peptidase substrate (FRET) analysis. See references below for more information.
Application:
Can be used with EDANS-DABCYL M0530, M0532 fluorophore-quencher pairs for labeling peptides and monitoring endo-peptidase activities.
References:
Shakhsher, Z.M., Seitz, W.R., Anal.Chem. 62 (1990) 1758."Design and Synthesis of New Fluorogenic HIV Protease Substrates Based on Resonance Energy Transfer." Wang G.T., et al., Tetrahedron Lett. 31: 6493 (1990).
"A general method for the preparation of internally quenched fluorogenic protease substrates using solid-phase peptide synthesis." Maggiora L.L., Smith C.W., Zhang Z.Y.. J. Med. Chem. 35: 3727-3730 (1992).
Keywords:
Aminoethylamino, Naphthalenesulfonic Acid, Naphthalenesulfonic, EDANS, Marker Gene 
