Molecular Weight: 470.52

Storage: F, D

Soluble: H₂O, DMSO

Molecular Formula: C₂₁H₁₈N₄O₅S₂

CAS Number: [N/A]

Alternative Name: To Be Discontinued

Unit Price (USD): 2 mg $201.19

Bulk Price/unit (when you buy 5 or more): $160.95

Description:
This protected glycine derivative produces the chemiluminescent compound 6-Amino-D-Luciferin M0352 upon peptidase enzymatic reaction. Subsequent analysis using the firefly luciferase detection system, provides an ultrasensitive method of measuring peptidase activity in vitro. Aminoluciferin is a very sensitive substrate of firefly luciferase and can be easily quantified in a luminometric assay.

References:

• "Synthesis and characterization of a bioluminogenic substrate for alpha-chymotrypsin." Monsees, T., Miska, W., Geiger, R., Anal. Biochem. 221 (1994):329-334.

• "Amino Analogs of Firefly Luciferin and Biological Activity Thereof." White, E.H., Worther, H., Seliger, W.D., J. Amer. Chem. Soc. (1966)88:2015-2019.