Marker Gene Technologies : M0520 -

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M0520 - Cyclic adipoyl-(6-amino)hexanoyl-DEVD-rhodamine 110, triethylamine salt
This product has been discontinued.

Molecular Weight: 1315.63

Storage: F, D

[C=Cold D=Desiccated F=Frozen L=Light Sensitive RT=Room Temperature]

Soluble: DMF, DMSO.

Molecular Formula: C₆₈H₁₀₂O₁₆N₁₀

Description:
A new in vivo caspase 3 substrate for intracellular apoptosis detection. See the references below for more details on use.

Note:
Make solution in organic solvents prior to dissolving in media for cellular labeling studies. Caspase 3 activity releases R110, EX: 492nm (e=88K) EM: 521nm

References:

"Synthesis of a macrocyclic rhodamine 110 enzyme substrate as an intracellular probe for caspase 3 activity.” Guzikowski AP, Naleway JJ, Shipp CT, Shutte RC. Tett. Lett. 41 (2000) 4733-4735.
"Cyclic Peptidase Substrates for Fluorescent Analysis of Caspase 3 Enyzme Activity" Guzikowski AP, Naleway JJ, Shipp CT, Shutte RC. Howard RA, Braden MR. (2000) Proc. SPIE 3913:54-63.

Keywords:

Cyclic adipoyl-(6-amino)hexanoyl-DEVD-rhodamine 110, triethylamine salt, triethylamine, 110, rhodamine, Marker Gene

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