Molecular Weight: 306.36
Storage: F, D
[C=Cold D=Desiccated F=Frozen L=Light Sensitive RT=Room Temperature]
Molecular Formula: C13H12N2O3S2
CAS Number: [N/A]
Alternative Name: Ethyl 4,5-dihydro-2[6-hydroxy-2-benzthiazolyl]-4-thiazole carboxylate
Unit Price (USD):
2 mg $57.90
Bulk Price/unit (when you buy 5 or more): $46.32
Description:
Membrane permeable analog of the primary substrate for the firefly luciferase light producing system with 30% higher light intensity.
Note:
The esterification of the D-luciferin carboxyl group increases the uptake of the substrate by intact mammalian cells in live-cell luciferase assays.
References:
- "Membrane-permeable Luciferin Esters for Assay of Firefly Luciferase in Live Intact Cells." F.F. Graig, et al. Biochem. J. 276: 637 (1991).
- "Applications of the Direct Imaging of Firefly luciferase Expression in Single Intact Mammalian Cells Using Charge-coupled Device Cameras." M.R.H. White, et al.Bioluminescence and Chemiluminescence: Current Status. P.E. Stanley and L.J. Kricka (Eds), John Wiley, Chichester, pp. 357-360.
- "CCD Imaging of Luciferase Gene Expression in Single Mammalian Cells." C.E. Hooper, et al. J. Bioluminescence and Chemiluminescence. 5:123 (1990).
- "Real-time Analysis of the Transcriptional Regulation of HIV and hCMV Promoters in Single Mammalian Cells." M.R.H. White, et al. J. of Cell Science 108:441 (1995)
Keywords:
D-Luciferin, ethyl ester, Luciferin, ethyl, ester, Ethyl dihydio-hydroxy-benzthiazolyl-thiazole carboxylate, dihydio, hydroxy, benzthiazolyl, thiazole, carboxylate, Marker Gene
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