Molecular Weight: 598.74
Storage: C
[C=Cold D=Desiccated F=Frozen L=Light Sensitive RT=Room Temperature]
Soluble: DMSO, DMF, EtOH
Absorption: (in nm) 495
Emission: (in nm) 520
Molecular Formula: C35H56BrN3
CAS Number: [75168-16-0]
Alternative Name: Acridine orange-10-octadecyl bromide
Unit Price (USD):
20 mg $106.95
Bulk Price/unit (when you buy 5 or more): $85.56
Description:
Useful fluorescent mitochondrial membrane probe used to analyze mitochondria by flow cytometry and measure changes in mitochondrial mass during apoptosis.
References:
Ratinaud MH, Leprat P, Julien R. (1988) "In situ flow cytometric analysis of nonyl acridine orange-stained mitochondria from splenocytes."Cytometry 9: 206.
Maftah A, Petit JM, Julien R. (1990) "Specific interaction of the new fluorescent dye 10 N-nonyl acridine orange with inner mitochondrial membrane. A lipid-mediated inhibition of oxidative phosphorylation."FEBS Lett. 260: 236.
Kessel, D., (1991) "Characterization of multidrug resistance by fluorescent dyes." Cancer Res. 51: 4665.
Cossarizza, A., (1994) "Mitochondrial modifications during rat thymocyte apoptosis: a study at the single cell level." Exp. Cell Res. 214: 323.
"Investigation of potential-sensitive fluorescent dyes for application in nitrate sensitive polymer membranes." Mohr GJ, Lehmann F, Ostereich R, Murkovic I, Wolfbeis OS. J Anal Chem 357(3): 284-291 (1997)."Fluorescent potential-sensitive dyes for use in solid state sensors for potassium ion." Murkovic I, Lobnik A, Mohr GJ, Wolfbeis OS. Anal Chim Acta 334(1-2): 125-132 (1996)."Effects of an aliphatic tail on the interactions of an ionic dye and a polyelectrolyte. The system of N-alkylated acridine orange derivatives and poly(styrenesulfonic acid)." Yamagishi A, Watanabe F. J Phys Chem 85(14): 2129-2134 (1981)."Selective activation of reactant molecules by reversed micelles." Yamagishi A, Masui T, Watanabe F. J Phys Chem 85(3): 281-285 (1981)."Distinguishing of molecular size by micelles." Yamagishi, A. Koen Yoshishu - Bunshi Kozo Sogo Toronkai: 50-51 (1979).
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