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M1197 - 3,3-Dioctadecyloxacarbocyanine perchlorate (DiO; DiOC18(3))
(Benzoxazolium, 3-octadecyl-2-[3-(3-octadecyl-2(3H)- benzoxazolylidene)-1-propenyl]-, perchlorate)


Molecular Weight: 881.72

Storage: F, D, L

[C=Cold D=Desiccated F=Frozen L=Light Sensitive RT=Room Temperature]

Soluble: CHCl3, DMSO, DMF

Absorption: (in nm) 484

Emission: (in nm) 504

Extinction (103): 139

Molecular Formula: C53H85ClN2O6

CAS Number: [34215-57-1]

Alternative Name: Benzoxazolium, 3-octadecyl-2-[3-(3-octadecyl-2(3H)- benzoxazolylidene)-1-propenyl]-, perchlorate

Unit Price (USD): 25 mg $50.13

Bulk Price/unit (when you buy 5 or more): $40.10

Description:
Highly fluorescent membrane probe for labeling live and fixed cells in culture.

Note:
High Purity Grade (>99%, TLC)

Application:
Long-chain dialkylcarbocyanines are widely used as anterograde and retrograde neuronal tracers in living and fixed tissues and cells.

References:

  • Gordon S.P., Berezhna S., Scherfeld D., Kahya N., Schwille P. (2005) "Characterization of interaction between cationic lipid-oligonucleotide complexes and cellular membrane lipids using confocal imaging and fluorescence correlation spectroscopy." Biophys. J. 88: 305-16
  • Wu C.C., Reilly J.F., Young W.G., Morrison J.H., Bloom F.E., (2004) "High-throughput morphometric analysis of individual neurons." Cereb. Cortex 14: 543-54
  • Adler M., Tritton T.R., (1988) "Fluorescence depolarization measurements on oriented membranes." Biophys. J. 53: 989-1005.
  • Sondermann J. (1971)"Darstellung Oberflachenaktiver Polymethincyanin-Farbstoffe mit Langen N-Alkyl-Ketten." Liebigs Ann. Chem. 749:183.

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