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M1269 - 1,1'-Dioctadecyl-3,3,3',3'-tetramethylindodicarbocyanine perchlorate
(DiIC18(5); DiD)


Molecular Weight: 959.9

Storage: F, D, L

[C=Cold D=Desiccated F=Frozen L=Light Sensitive RT=Room Temperature]

Soluble: CHCl3, MeOH, acetone, DMSO

Absorption: (in nm) 596

Emission: (in nm) 670

Extinction (103): 270

Molecular Formula: C61H99ClN2O4

CAS Number: [127274-91-3]

Alternative Name: DiIC18(5); DiD

Unit Price (USD): 10 mg $50.90

Bulk Price/unit (when you buy 5 or more): $40.72

Description:
Red fluorescent membrane probe for long term staining of live cells. Also used in fiber optic sensors for detecting K+ using fluorescence energy transfer.

References:

  • "Fibre optic sensor for the detection of potassium using fluorescence energy transfer." Roe JN, Szoka FC, Verkman AS., Analyst 115: 353-358 (1990).
  • "Carbocyanine dyes with long alkyl side-chains: broad spectrum inhibitors of mitochondrial electron transport chain activity." Anderson WM, Trgovcich-Zacok D., Biochem. Pharmacol. 49: 1303-1311 (1995).
  • "Optical sectioning-- slices of life." Paddock S., Science 295: 1319-1321 (2002).
  • "Photodamage to intact erythrocyte membranes at high laser intensities: methods of assay and suppression." Bloom JA, Webb WW., J. Histochem. Cytochem. 32: 608-616 (1984).
  • "Iontophoretic dye labeling of embryonic cells." Fraser SE., Methods Cell. Biol. 51: 147-160 (1996).
  • "Multicolor "DiOlistic" labeling of the nervous system using lipophilic dye combinations." Gan WB, Grutzendler J, Wong WT, Wong RO, Lichtman JW., Neuron 27: 219-225 (2000).
  • "Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy." Evans CL, Potma EO, Puoris'haag M, Cote D, Lin CP, Xie XS., Proc. Natl. Acad. Sci. U. S. A. 102: 16807-12 (2005).
  • "Rapid labeling of neuronal populations by ballistic delivery of fluorescent dyes." Grutzendler J, Tsai J, Gan WB. Methods 30: 79-85 (2003).
  • "Lateral Diffusion of Lipids and Proteins in Bilayer Membranes." Vaz WLC, Goodsaid-Zaluondo, F., Jacobson K., FEBS Lett. 174: 199 (1984).

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