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Vectors Vectors
OliGlo OliGloTM Nucleic Acid Labeling Kits
Enzyme Substrates and Kits Enzyme Substrates and Kits
Enzyme Inhibitors Enzyme Inhibitors
MGT Detection Kits MGT Detection Kits
Cell Regulatory Substrates Cell Regulatory Substrates
Special Labeling Reagents Special Labeling Reagents
Lipids Lipids
Carbohydrates/Oligosaccharides Carbohydrates/Oligosaccharides  
Fluorescent Reagents Fluorescent Reagents
Enzyme Substrates and Kits for Protease Enzymes.

Proteases are a family of enzymes that cleave proteins and peptides at site-specific peptide linkages within their structures. They are further classified as either endopeptidases, which cleave proteins or peptides at internal peptide linkages, or exopeptidases, which can cleave the terminal amino-acid residues from peptides or proteins. Marker Gene sells a variety of chromogenic, fluorogenic or secondary enzyme specific protease substrates or kits for use in assay development and research. Many of these substrates and kits are specific for important intracellular enzymes such as the Caspases, Calpains, Cathepsins used in apoptosis reasearch. Please see the list below for more information about individual products.

  ID   Name   CAS Unit Size Price Bulk Price (5+)
M1060   L-Leucine 7-amido-4-methyl coumarin hydrochloride (Leu-AMC.HCl) 62480-44-8 25 mg 110.91 88.73
Sensitive fluorogenic substrate for leucine aminopeptidase which releases a bright blue fluorescent dye, 7-amino-4-methylcoumarin M1059 upon enzyme activity (excitation 380nm emission 440nm).
M1319   MarkerGene™ Fluorescent Protease Assay Kit 1 kit 170.10 136.08
Allows quick and simple measurement of general protease activity in biological samples.
M0353   N-CBZ-β-glycinyl-6-aminoluciferin 1233518-28-9 2 mg 211.25 169.00
Protected glycine derivative produces the chemiluminescent compound 6-Amino-D-Luciferin Product M0352 upon peptidase enzymatic reaction.
M0843   Magic Red™-(FR)2 Cathepsin L Assay Kit 25tests N/A 1 kit 166.95 166.95
These Magic Red™ substrate-based assays are designed to detect Cathepsin protease activity within whole living cells, using fluorescence microscopy.
M0844   Magic Red™-(FR)2 Cathepsin L Assay Kit 100tests N/A 1 kit 413.70 413.70
These Magic Red™ substrate-based assays are designed to detect Cathepsin protease activity within whole living cells, using fluorescence microscopy.
M0841   Magic Red™-(LR)2 Cathepsin K Assay Kit 25tests N/A 1 kit 166.95 166.95
These Magic Red™ substrate-based assays are designed to detect Cathepsin protease activity within whole living cells, using fluorescence microscopy.
M0839   Magic Red™-(RR)2Cathepsin B Assay Kit 25tests N/A 1 kit 166.95 166.95
These Magic Red™ substrate-based assays are designed to detect Cathepsin protease activity within whole living cells, using fluorescence microscopy.
M0840   Magic Red™-(RR)2 Cathepsin B Assay Kit 100tests N/A 1 kit 413.70 413.70
These Magic Red™ substrate-based assays are designed to detect Cathepsin protease activity within whole living cells, using fluorescence microscopy.
M0833   Red Sulforhodamine Poly Caspases Detection Kit 25tests N/A 1 kit 193.20 193.20
SR-FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases.
M0834   Red Sulforhodamine Poly Caspases Detection Kit 100tests N/A 1 kit 518.70 518.70
SR-FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases.
M0815   Green FAM Poly Caspases Assay Kit 25 tests N/A 1 kit 177.45 177.45
FAM FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases intracellularly.
M0816   Green FAM Poly Caspases Assay Kit 100tests N/A 1 kit 487.20 487.20
FAM FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases intracellularly.
M0827   Green FAM Caspase 9 Assay Kit 25tests N/A 1 kit 177.45 177.45
FAM FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases intracellularly.
M0828   Green FAM Caspase 9 Assay Kit 100tests N/A 1 kit 487.20 487.20
FAM FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases intracellularly.
M0825   Green FAM Caspase 8 Assay Kit 25tests N/A 1 kit 177.45 177.45
FAM FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases intracellularly.
M0826   Green FAM Caspase 8 Assay Kit 100tests N/A 1 kit 487.20 487.20
FAM FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases intracellularly.
M0823   Green FAM Caspase 6 Assay Kit 25tests N/A 1 kit 177.45 177.45
FAM FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases intracellularly.
M0824   Green FAM Caspase 6 Assay Kit 100tests N/A 1 kit 487.20 487.20
FAM FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases intracellularly.
M0821   Green FAM Caspases 3 and 7 Assay Kit 25tests N/A 1 kit 177.45 177.45
FAM FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases intracellularly.
M0835   Red Sulforhodamine Caspases 3 and 7 Assay Kit 25tests
M0837   Magic Red™-(DEVD)2 Caspases 3 and 7 Assay Kit 25tests N/A 1 kit 166.95 166.95
Magic Red™ products are substrate-based assays designed to detect protease activity within whole living cells, using a fluorescence microscope.
M0822   Green FAM Caspases 3 and 7 Assay Kit 100tests N/A 1 kit 487.20 487.20
FAM FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases intracellularly.
M0836   Red Sulforhodamine Caspases 3 and 7 Assay Kit 100tests
M0838   Magic Red™-(DEVD)2 Caspases 3 and 7 Assay Kit 100tests N/A 1 kit 413.70 413.70
Magic Red™ products are substrate-based assays designed to detect protease activity within whole living cells, using a fluorescence microscope.
M0819   Green FAM Caspase 2 Assay Kit 25tests N/A 1 kit 177.45 177.45
FAM FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases intracellularly.
M0820   Green FAM Caspase 2 Assay Kit 100tests N/A 1 kit 487.20 487.20
FAM FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases intracellularly.
M0831   Green FAM Caspase 13 Assay Kit 25tests N/A 1 kit 177.45 177.45
FAM FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases intracellularly.
M0832   Green FAM Caspase 13 Assay Kit 100tests N/A 1 kit 487.20 487.20
FAM FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases intracellularly.
M0829   Green FAM Caspase 10 Assay Kit 25tests N/A 1 kit 177.45 177.45
FAM FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases intracellularly.
M0830   Green FAM Caspase 10 Assay Kit 100tests N/A 1 kit 487.20 487.20
FAM FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases intracellularly.
M0817   Green FAM Caspase 1 Assay Kit 25tests N/A 1 kit 177.45 177.45
FAM FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases intracellularly.
M0818   Green FAM Caspase 1 Assay Kit 100tests N/A 1 kit 487.20 487.20
FAM FLICA™ Apoptosis Detection Kits use a novel approach to detect active caspases intracellularly.
M0846   MitoPT™ Apoptosis Detection Kit 400tests N/A 1 kit 350.70 350.70
Use of the MitoPT™ kit allows the easy distinction between non-apoptotic red fluorescent cells and apoptotic green fluorescent cells.
M0845   MitoPT™ Apoptosis Detection Kit 100tests N/A 1 kit 182.70 182.70
Use of the MitoPT™ kit allows the easy distinction between non-apoptotic red fluorescent cells and apoptotic green fluorescent cells.

©2012 Marker Gene Technologies, Inc. Published by Marker Gene Technologies, Inc., The University of Oregon Riverfront Research Park, 1850 Millrace Drive, Eugene, Oregon 97403-1992 USA. All rights reserved. For information on the use or copying of the material contained in this document, please contact us at techservice@markergene.com.