alpha-DGal(1-4)DGal - CETE - BSA Conjugate

Product ID: M0169



Unit SizePriceQuantity 
1mg
$296.30
  • Buy 5 for $237.04 each and save 21%

Availability: In stock


Description

Synthetic E. coli receptor of the P1 blood group antigen.

This synthetic disaccharide represents a portion of the P1 blood group antigen that is responsible for E. coli adhesion to surface membranes of the intestinal tract. Bound to Bovine Serum Albumin (BSA), it is a useful antigen for immunological studies or as an inhibitor of adhesion of endothelial cell binding to uropathogenic E. coli strains.

Technical Data
SKU M0169
Unit Size 1mg
Alternative Names P1 Blood Group Antigen-Bacterial Receptor, Carboxyethylthioethyl 4-O-alpha-D-Galactopyranosyl-beta-D-Galactopyranoside-Bovine serum Albumin Conjugate
Molecular Weight 77000
Notes D.O.S: 21/BSA

References and Citations

Citations:

  • Mitsumori K, Terai A, Yamamoto S, Ishitoya S, Yoshida O. (1999) "Virulence characteristics of Eschevichia coli in acute bacterial prostatitis." J Infect Dis 180(4): 1378-1381. doi: 10.1086/314976.
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References:

  • Johnson JR, Ross AE. (1993) "P1-antigen-containing avian egg whites as inhibitors of P adhesins among wild-type Escherichia coli strains from patients with urosepsis." Infect Immun 61(11): 4902-5.
  • Nilsson S, Lönn H, Norberg T. (1991) "Synthesis of the trisaccharide, 2-(p-trifluoroacetamidophenyl)ethyl O-alpha-D-galactopyranosyl-(1-4)-O-beta-D-galactopyranosyl-(1-4)-2-acet amido-2-deoxy-beta-D-glucopyranoside, corresponding to the blood group P1 determinant." Glycoconj J 8(1): 9-15.
  • Bock K, Breimer ME, Brignole A, Hansson GC, Karlsson KA, Larson G, Leffler H, Samuelsson BE, Stromberg N, Eden CS. (1985) "Specificity of binding of a strain of uropathogenic Escherichia coli to Gal alpha 1----4Gal-containing glycosphingolipids." J Biol. Chem. 260(14): 8545-8551.
  • Dahmen J, Frejd T, Magnusson G, Noori G, Carlstrom AS. (1984) "Synthesis of spacer-arm, lipid, and ethyl glycosides of the terminal trisaccharide [alpha-D-Gal-(1----4)-beta-D-Gal-(1----4)-beta-D-GlcNAc] portion of the blood-group P1 antigen: preparation of neoglycoproteins." Carbo. Res. 129: 63-71.
  • Eden CS, Freter R, Hagberg L, Hull R, Hull S, Leffler H, Schoolnik G. (1982) "Inhibition of experimental ascending urinary tract infection by an epithelial cell-surface receptor analogue." Nature 298(5874): 560-562.
  • Leffler H, Eden CS. Scand. (1980) "Glycosphingolipids of human urinary tract epithelial cells as possible receptors for adhering Escherichia coli bacteria." J. Infect. Dis. Suppl. 24: 144-147.
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