Biocytin hydrazide hydrochloride

Product ID: M0128



Unit SizePriceQuantity 
10mg
$65.82
  • Buy 5 for $52.66 each and save 21%

Availability: In stock


Description

Water-soluble, long-chained, biotin-containing hydrazide, used for the selective detection of glycoconjugates.

Biocytin hydrazide is an aldehyde-fixable cellular tracer that can be introduced into cells by microinjection. Biocytin hydrazide can also be used to label glycoproteins or other carbohydrate molecules. Biocytin hydrazide is a selective label for sialic acids, galactose, and other sugars in glycoconjugates using avidin-biotin technology. Can also be used to biotin label peptides and proteins. Biocytin hydrazide contains an extra linking arm allowing for easier binding to avidin or streptavidin in ELISA type applications.

Technical Data
SKU M0128
CAS Number 102743-85-1
Unit Size 10mg
Molecular Formula C₁₆H₃;₀N₆O₃SHCl
Molecular Weight 386.5
Soluble In DMF
Storage Conditions -20C, Desiccated
Notes Purity: > 95%

References and Citations

References:

  • Ouadia A, Karamanos Y, Julien R.(1992) "Detection of the ganglioside N-glycolyl-neuraminyl-lactosyl-ceramide by biotinylated Escherichia coli K99 lectin." Glycoconj. J 9: 21-26 (1992).
  • Wilchek M, Bayer EA (1988) "The avidin-biotin complex in bioanalytical applications." Anal. Biochem. 171: 1-32.
  • Bayer EA, Ben-Hur H, Wilchek M. (1988) "Biocytin hydrazide-a selective label for sialic acids, galactose, and other sugars in glycoconjugates using avidin-biotin technology." Anal. Biochem. 170: 271-281.
  • Roffman E, Meromsky L, Ben-Hur H, Bayer EA, Wilchek M. (1986) "Selective labeling of functional groups on membrane proteins or glycoproteins using reactive biotin derivatives and 1251-streptavidin." Biochem. Biophys. Res. Commun. 136: 80-85.
  • Roffman E, Wilchek M. (1986) "Selective covalent modification of newly synthesized activation-induced sialoglycoconjugates on the T lymphocyte membrane." Biochem. Biophys. Res. Commun. 135: 473-479.
  • Roffman E, Wilchek M. (1986) "Lymphocyte activation by oxidation modification: avidin-modified T cells activate biotin-modified autologous T cells but no vice versa." Cell. Immunol. 103: 140-146.
  • Roffman E, Wilchek M. (1986) "The extent of oxidative mitogenesis does not correlate with the degree of aldehyde formation of the T lymphocyte membrane." J Immunol. 137: 40-44.
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