Cells and their organelles are all defined by hydrophobic, lipid-rich membranes. The lipid bilayers function to partition their contents, organize receptors in microdomains and influence cell function. By attaching fluorescent probes to lipids, specific targeting to the hydrophobic lipid interiors is achieved. Marker Gene offers a panel of lipid probes, including one of our most popular kits, the MarkerGene™ Membrane Fluidity Kit.
This kit allows fast and easy measurement of lipase activity in vitro, in cell preparations or in vivo using the fluorescent triglyceride substrate 1,2-dioleoyl-3-(pyren-1-yl)decanoyl-rac-glycerol M0258. Learn More
Fluorescent probe for conformation and quantitation studies of proteins. It is practically nonfluorescent in water, becoming fluorescent when bound to membranes (q.y. ~0.27) or proteins (q.y. ~0.72). Learn More
Ambiphilic probe with a polar, environmentally-sensitive dansyl fluorophore attached to a long chain fatty acid. The polar dansyl headgroup partitions to the surface of lipid bilayer membranes while the fatty acid portion embeds into lipid bilayers or can attach to fatty acid carrier protein lipidic environments. Learn More
DiOC₆(3) is a cell-permeant, lipophilic dye that stains internal membranes of both live and fixed cells, such as the mitochondrial, Golgi and endoplasmic reticulum membranes. Staining patterns are concentration dependent. Learn More