Cell Membranes

Cells and their organelles are all defined by hydrophobic, lipid-rich membranes. The lipid bilayers function to partition their contents, organize receptors in microdomains and influence cell function. By attaching fluorescent probes to lipids, specific targeting to the hydrophobic lipid interiors is achieved. Marker Gene offers a panel of lipid probes, including one of our most popular kits, the MarkerGene™ Membrane Fluidity Kit.

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  1. 4-Trifluoromethylumbelliferone (TFMU)

    4-Trifluoromethylumbelliferone (TFMU)


    This slightly longer wavelength analog of 4-methylcoumarin (4-MU) has a pKa that more closely matches physiological pH values. Learn More
  2. MarkerGene™ Membrane Fluidity Kit

    MarkerGene™ Membrane Fluidity Kit


    This kit allows quantitative monitoring of membrane fluidity in cell membranes, micelles, and vesicles through use of a lipophilic pyrene probe. Learn More
  3. MarkerGene™ Fluorescent Lipase Assay Kit

    MarkerGene™ Fluorescent Lipase Assay Kit


    This kit allows fast and easy measurement of lipase activity in vitro, in cell preparations or in vivo using the fluorescent triglyceride substrate 1,2-dioleoyl-3-(pyren-1-yl)decanoyl-rac-glycerol M0258. Learn More
  4. 6-p-Toluidino-2-naphthalenesulfonic acid

    6-p-Toluidino-2-naphthalenesulfonic acid


    Fluorescent probe for conformation and quantitation studies of proteins. It is practically nonfluorescent in water, becoming fluorescent when bound to membranes (q.y. ~0.27) or proteins (q.y. ~0.72). Learn More
  5. DiO (3,3-Dioctadecyloxacarbocyanine perchlorate)

    DiO (3,3-Dioctadecyloxacarbocyanine perchlorate)


    Highly fluorescent membrane probe for labeling live and fixed cells in culture. DiO has been used in long-term neuronal tracing studies. Learn More
  6. DAUDA (Dansyl-11-aminoundecanoic acid)

    DAUDA (Dansyl-11-aminoundecanoic acid)


    Ambiphilic probe with a polar, environmentally-sensitive dansyl fluorophore attached to a long chain fatty acid. The polar dansyl headgroup partitions to the surface of lipid bilayer membranes while the fatty acid portion embeds into lipid bilayers or can attach to fatty acid carrier protein lipidic environments. Learn More
  7. DiR (1,1'-Dioctadecyl-3,3,3',3'-tetramethylindotricarbocyanine iodide)

    DiR (1,1'-Dioctadecyl-3,3,3',3'-tetramethylindotricarbocyanine iodide)


    Lipophilic near-IR (NIR) fluorescent membrane probe useful for labeling cells for long term analysis. Learn More
  8. DiOC₆(3)



    DiOC₆(3) is a cell-permeant, lipophilic dye that stains internal membranes of both live and fixed cells, such as the mitochondrial, Golgi and endoplasmic reticulum membranes. Staining patterns are concentration dependent. Learn More

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