| Product ID |
Product Name |
Description |
| M0149 |
Dexamethasone-21-O-ß-D-Galactopyranoside |
Cleavage product: Upon enzymatic or chemical hydrolysis of the galactoside group, dexamethasone is produced. Dexamethasone is a useful inducer of gene expression when combined with a dexamethasone-inducible promoter system, and is also a potent glucocorticoid anti-inflammatory. Dexamethasone has also been used as an inducer of apoptosis in tumor cells. |
| M0165 |
Chloramphenicol ß-D-Galactoside |
Cleavage product: Upon enzymatic or chemical hydrolysis of the galactoside group, chloramphenicol, an antibiotic (bacteriostatic), is produced. |
| M0174 |
5-Fluorouridine 5-O-ß-D-Galactopyranoside |
This analog of 5-fluorouridine (5-FUR) is useful for lacZ specific release of 5-FUR in recombinant cells or tissues. 5-FUR is a potent anti-metabolite, with mode of action by inhibition of thymidylate synthetase or by incorporation into RNA in vivo. |
| M0176 |
Tetracycline 10-O-ß-D-Galactopyranoside |
Tetracycline analog useful as an antibiotic for specific release in lacZ transfected cells and tissues. |
| M0182 |
7-N-Benzoyl-Cephalosporanic acid, L-glutamate ester |
This conjugate of Cephalosporin C and glutamate is useful for release of the essential amino-acid L-glutamate, upon action of ampicillinase (beta-lactamase activity) in amp-positive cell lines from vectors incorporating the amp (selection) marker gene. |
| M0220 |
1,2-di-O-Octanoyl Galactopyranosyl rac-glycerol |
This synthetic diglyceride analog is an activator of protein kinase C, that is released upon action of beta-galactosidase in lacZ transfected cells and tissues. |
| M0224 |
1-O-Oleoyl-2-O-acetyl-3-O-ß-D-Galactopyranosyl syn-Glycerol |
This synthetic diglyceride analog is an activator of protein kinase C, that is released upon action of beta-galactosidase in lacZ transfected cells and tissues. |
| M0304 |
Pyridoxine Galactoside |
This pyridoxine (vitamin B6) analog is a useful tissue culture component that will release pyridoxine upon action of lacZ beta-galactosidase. |
| M0326 |
Myo-inositol galactoside |
This galactoside derivative of myo-inositol will release myo-inositol upon action of beta-galactosidase. myo-Inositol is a component of membrane phospholipids, glycophosphatidylinositol anchors that bind glycoproteins to cell membranes and a precursor of inositol phosphates that act as second messengers in vivo. This derivative can also be used as a tissue culture media component that will be selectively released in lacZ transfected cell lines. |
| M0328 |
Riboflavin galactoside |
This analog of riboflavin (vitamin B2) releases riboflavin upon action of beta-galactosidase enzyme activity. Riboflavin is a common component of tissue culture media and M0328 can be used to select for lacZ transfected cells in culture. |
| M0330 |
Pyridoxal galactoside |
This pyridoxine (vitamin B6) analog is a useful tissue culture media component that will release pyridoxal upon action of lacZ beta-galacotsidase. Useful as a media component for selection of lacZ positive cells in culture. |
| M0338 |
Pantothenic acid 2,4-di-O-ß-D-Galactopyranoside |
This analog of pantothenic acid (vitamin B5) releases pantothenic acid upon action of beta-galactosidase enzyme activity. Pantothenic acid is a common component of tissue culture media and M0338 can be used to select for lacZ transfected cells in culture. |
| M0351 |
Thiamine Galactoside |
This thiamine (vitamin B1) analog is a useful tissue culture component that will release thiamine upon action of lacZ beta-galacotsidase activity. Useful for selection of lacZ transfected cell lines in culture. |
| M0630 |
Bromoxynil glucuronic acid triacetate methyl ester |
Bromoxynil is a nitrile herbicide that is used for post-emergent control of annual broadleaf weeds. It is especially effective in the control of weeds in cereal, corn, sorghum, onions, flax and mint. This bromoxynil derivative can be used for selective release in GUS-positive plant systems, in a tissue specific manner. The compound works by inhibiting photosynthesis in the target plants. This beta-glucuronide derivative lacks activity until acted upon by intracellular beta-glucuronidase (cloned with the GUS marker gene). Additional ester groups help with cell permeation of this herbicide derivative. |
| M0632 |
Bromoxynil glucuronic acid methyl ester |
Bromoxynil is a nitrile herbicide that is used for post-emergent control of annual broadleaf weeds. It is especially effective in the control of weeds in cereal, corn, sorghum, onions, flax and mint. This bromoxynil derivative can be used to selectively ablate GUS-positive cells and tissues in plant systems. The compound works by inhibiting photosynthesis in the target plants. This beta-glucuronide derivative lacks activity until acted upon by intracellular beta-glucuronidase (cloned with the GUS marker gene). The methyl ester helps with cell permeation in vivo. |
