Chloramphenicol β-D-galactoside

Product ID: M0165



Unit SizePriceQuantity 
2mg
$131.65
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Availability: In stock


Description

Upon enzymatic or chemical hydrolysis of the galactoside group, chloramphenicol, an antibiotic (bacteriostatic), is produced.

Chloramphenicol, also known as chlornitromycin, is an effective antibiotic useful against a wide variety of Gram-positive and Gram-negative bacteria, including most anaerobic organisms. This analog of chloramphenicol contains a galactose conjugated to the active site of action which, upon enzymatic or chemical hydrolysis of the galactoside group, releases the active chloramphenicol.

Technical Data
SKU M0165
CAS Number 191476-32-1
Unit Size 2mg
Absorption 278nm
Molecular Formula C₁₇H₂₂N₂O₁₀Cl₂
Molecular Weight 485.27
Soluble In DMSO, H2O
Storage Conditions -20C, Desiccated
Notes For research purposes only! Not for drug or human use!

References and Citations

References:

  • Scheckermann C, Wagne F, Fischer L. (1997) "Galactosylation of antibiotics using the β-​galactosidase from Aspergillus oryzae." Enzyme and Microbial Technology  20(8) 629-634.
  • Gill I, Valivet R. (2000) "Enzymatic glycosylation in plasticized glass phases: a novel and efficient route to O-​glycosides." Angewandte Chemie, International Edition, 39(21), 3804-3808.
  • Janin YL, Zoltobroda G, Huel C,Monneret C. (2002)" Synthesis of chloramphenicol and mandelonitrile galactose-​containing prodrugs." Journal of Carbohydrate Chemistry 21(4), 275-286.
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