Cytochrome P450

The cytochrome P-450s are a large group of monooxygenase enzymes responsible for the metabolism of toxins in the body. These enzymes, requiring NADPH as a cofactor and O2 as co-substrate, are located in the endoplasmic reticulum and are highly concentrated in the liver and small intestine. Additionally, Cytochrome P-450s are also found in the mitochondrial membrane. P-450 enzymes encompass a highly diverse

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  1. 6-Chloro-indolyl β-D-glucuronic acid, lithium salt

    6-Chloro-indolyl β-D-glucuronic acid, lithium salt

    $83.39

    Chromogenic substrate for β-D-Glucuronidase(GUS). Learn More
  2. Resorufin 7-O-methyl ether

    Resorufin 7-O-methyl ether

    $138.95

    One of the most popular substrates for analysis of microsomal dealkylase and cytochrome P450 enzymes. Learn More
  3. Resorufin ethyl ether

    Resorufin ethyl ether

    $151.72

    Microsomal dealkylase and Cytochrome P450 enzyme substrate. Releases the red fluorophore resorufin (Abs. 571 nm; Em. 585 nm) upon enzyme reaction. Routinely used to differentiate the various cytochrome P450 isoforms. Learn More
  4. 7-Methoxycoumarin

    7-Methoxycoumarin

    $75.66

    Fluorogenic Cytochrome P450 and microsomal dealkylase substrate for differentiation of several isoforms of these enzymes producing a blue fluorescence emission upon enzyme activity. Learn More

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