DAUDA (Dansyl-11-aminoundecanoic acid)
Product ID: M1249
Ambiphilic probe with a polar, environmentally-sensitive dansyl fluorophore attached to a long chain fatty acid. The polar dansyl headgroup partitions to the surface of lipid bilayer membranes while the fatty acid portion embeds into lipid bilayers or can attach to fatty acid carrier protein lipidic environments.
|Alternative Names||11-[5-(Dimethylamino)-1-naphthalenesulfonylamino]undecanoic acid; DAUDA|
|Soluble In||CHCl3, CH2Cl2, DMSO, DMF|
|Storage Conditions||2-8C, Desiccated|
- Moules IK, Rooney EK, Lee AG. (1982) "Binding of amphipathic drugs and probes to biological membranes." FEBS Lett 138: 95-100.
- Rooney EK, East JM, Jones OT. (1983) "Interaction of Fatty Acids with Lipid Bilayers." Biochim Biophys Acta 728:159.
- Stubbs CD, Meech SR, Lee AG, Phillips D. (1985) "Solvent relaxation in lipid bilayers with dansyl probes." Biochim Biophys Acta 815: 351-360.
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- Wilton DC (1990) "The fatty acid analogue 11-(dansylamino)undecanoic acid is a fluorescent probe for the bilirubin-binding sites of albumin and not for the high-affinity fatty acid-binding sites." Biochem J 270, 163-166.
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- Buckland AG, Heeley EL, Wilton DC (2000) "Bacterial cell membrane hydrolysis by secreted phospholipases A(2): a major physiological role of human group IIa sPLA(2) involving both bacterial cell wall penetration and interfacial catalysis." Biochim Biophys Acta 1484:195-206.
- Gasymov OK, Abduragimov AR, Yusifov TN, Glasgow BJ (2001) "Site-directed tryptophan fluorescence reveals the solution structure of tear lipocalin: evidence for features that confer promiscuity in ligand binding." Biochemistry 40: 14754-14762.
- Bezzine S, Bollinger JG, Singer AG, Veatch SL, Keller SL, Gelb MH (2002) "On the Binding Preference of Human Groups IIA and X Phospholipases A2 for Membranes with Anionic Phospholipids." J Biol Chem 277: 48523-48534.
- Ramos CR, Figueredo RC, Pertinhez TA, Vilar MM, do Nascimento AL, Tendler M, Raw I, Spisni A, Ho PL (2003) "Gene structure and M20T polymorphism of the Schistosoma mansoni Sm14 fatty acid-binding protein. Molecular, functional, and immunoprotection analysis." J. Biol. Chem. 278: 12745-12751.
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