DiD (1,1'-Dioctadecyl-3,3,3',3'-tetramethylindodicarbocyanine perchlorate)

Product ID: M1269

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  • Buy 5 for $52.65 each and save 20%

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Red fluorescent membrane probe for long term staining of live cells, including neuronal tracing. Also used in fiber optic sensors for detecting K+ using fluorescence energy transfer.

This red fluorescent membrane probe can be used for long term staining of live cells, including neuronal tracing, due to the long chain (C-18) groups that embed into the plasma membrane of live cells. It has also been used in fiber optic sensors for detecting K+ using fluorescence energy transfer.

Technical Data
SKU M1269
CAS Number 127274-91-3
Unit Size 10mg
Alternative Names DiIC18(5)
Absorption 596nm
Emission Wavelength 670
Extinction 270
Detection Method Fluorescence
Molecular Formula C₆₁H₉₉ClN₂O₄
Molecular Weight 959.9
Soluble In CHCl3, MeOH, acetone, DMSO
Storage Conditions -20C, Desiccated, Protect From Light

References and Citations


  • "Fibre optic sensor for the detection of potassium using fluorescence energy transfer." Roe JN, Szoka FC, Verkman AS., Analyst 115: 353-358 (1990).
  • "Carbocyanine dyes with long alkyl side-chains: broad spectrum inhibitors of mitochondrial electron transport chain activity." Anderson WM, Trgovcich-Zacok D., Biochem. Pharmacol. 49: 1303-1311 (1995).
  • "Optical sectioning-- slices of life." Paddock S., Science 295: 1319-1321 (2002).
  • "Photodamage to intact erythrocyte membranes at high laser intensities: methods of assay and suppression." Bloom JA, Webb WW., J. Histochem. Cytochem. 32: 608-616 (1984).
  • "Iontophoretic dye labeling of embryonic cells." Fraser SE., Methods Cell. Biol. 51: 147-160 (1996).
  • "Multicolor "DiOlistic" labeling of the nervous system using lipophilic dye combinations." Gan WB, Grutzendler J, Wong WT, Wong RO, Lichtman JW., Neuron 27: 219-225 (2000).
  • "Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy." Evans CL, Potma EO, Puoris'haag M, Cote D, Lin CP, Xie XS., Proc. Natl. Acad. Sci. U. S. A. 102: 16807-12 (2005).
  • "Rapid labeling of neuronal populations by ballistic delivery of fluorescent dyes." Grutzendler J, Tsai J, Gan WB. Methods 30: 79-85 (2003).
  • "Lateral Diffusion of Lipids and Proteins in Bilayer Membranes." Vaz WLC, Goodsaid-Zaluondo, F., Jacobson K., FEBS Lett. 174: 199 (1984).
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