Molecular Weight: 392

Storage: F, D

Soluble: DMSO

Absorption: (in nm) 325

Emission: (in nm) 410

Extinction (10³): 13

Molecular Formula: C₁₆H₁₅O₈F₃

CAS Number: [117153-55-6]

Unit Price (USD): 25 mg $101.86

Bulk Price/unit (when you buy 5 or more): $81.49

Description:
Blue-green fluorogenic β-galactosidase substrate that has a lower pKa for higher fluorescence in the physiological pH range.

Note:
Cleavage product: Upon cleavage of galactose, trifluoromethylumbelliferone (TFMU), Product M0041

References:

• "4-Trifluoromethylumbelliferyl glycosides as new substrates for revealing diseases connected with hereditary deficiency of lysosome glycosidases." Karpova EA, Voznyi YaV, Dudukina TV, Tsvetkova IV. Biochem. Int. 24: 1135-1144 (1991).

• "4-Trifluoromethylumbelliferyl-B-D-Galactopyranoside: its synthesis and application as the fluorigenic substrate of beta-galactosidase E. coli for screening monoclonal antibodies by immunosorbent elisa." Yegorov AM, et al. Anal. Lett. 21: 193 (1988).

• "A new fluorescent detection system for identifying variant hemoglobins after gel electrophoresis using immunobinding with monoclonal antibodies." Smith RE. J Histochem. Cytochem. 34: 585 (1986).