Molecular Weight: 1315.63

Storage: F, D
[C=Cold D=Desiccated F=Frozen L=Light Sensitive RT=Room Temperature]

Soluble: DMF, DMSO.

Molecular Formula: C₆₈H₁₀₂O₁₆N₁₀

Description:
A new in vivo caspase 3 substrate for intracellular apoptosis detection. See the references below for more details on use.

Note:
Make solution in organic solvents prior to dissolving in media for cellular labeling studies. Caspase 3 activity releases R110, EX: 492nm (e=88K) EM: 521nm

References:

• "Synthesis of a macrocyclic rhodamine 110 enzyme substrate as an intracellular probe for caspase 3 activity.” Guzikowski AP, Naleway JJ, Shipp CT, Shutte RC. Tett. Lett. 41 (2000) 4733-4735.
• "Cyclic Peptidase Substrates for Fluorescent Analysis of Caspase 3 Enyzme Activity" Guzikowski AP, Naleway JJ, Shipp CT, Shutte RC. Howard RA, Braden MR. (2000) Proc. SPIE 3913:54-63.