Molecular Weight: 378.43

Storage: F, L
[C=Cold D=Desiccated F=Frozen L=Light Sensitive RT=Room Temperature]

Soluble: DMF, DMSO, MeOH

Absorption: (in nm) 466

Emission: (in nm) 530

Extinction (10³): 24

Molecular Formula: C₁₈H₂₆N₄O₅

CAS Number: [96801-39-7]

Alternative Name: 12-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)dodecanoic acid; NBD-aminododecanoic acid

Unit Price (USD): 100 mg $115.75

Bulk Price/unit (when you buy 5 or more): $92.60

Description:
A useful fluorescent probe for fatty acid and carrier protein binding sites.

References:

• "Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized." Tani M, Okino N, Mitsutake S, Tanigawa T, Izu H, Ito M. J Biol Chem 275: 3462-3468 (2000).
• "Probing the ligand binding sites of fatty acid and sterol carrier proteins: effects of ethanol." Schroeder F, Myers-Payne SC, Billheimer JT, Wood WG. Biochemistry 34(37): 11919-27 (1995).
• "Lateral diffusion of lipids in model and natural membranes." Tocanne JF, Dupou-Cezanne L, Lopez A. Prog Lipid Res 33: 203-237 (1994).
• "Large-scale preparation of asymmetrically labeled fluorescent lipid vesicles." Dao HN, McIntyre JC, Sleight RG. Anal Biochem 196: 46-53 (1991).
• "Human acid beta-glucosidase: use of inhibitors, alternative substrates and amphiphiles to investigate the properties of the normal and Gaucher disease active sites." Osiecki-Newman K, Fabbro D, Legler G, Desnick RJ, Grabowski GA. Biochim Biophys Acta 15: 87-100 (1987).
• "Prenatal diagnosis of Krabbe disease using a fluorescent derivative of galactosylceramide." Zeigler M, Zlotogora J, Regev R, Dagan A, Gatt S, Bach G. Clin Chim Acta 142: 313-318 (1984).
• "Gaucher type I (Ashkenazi) disease: a new method for heterozygote detection using a novel fluorescent natural substrate." Grabowski GA, Dinur T, Gatt S, Desnick RJ. Clin Chim Acta 124: 123-135 (1982).