Molecular Weight: 275.39

Storage: RT
[C=Cold D=Desiccated F=Frozen L=Light Sensitive RT=Room Temperature]

Soluble: DMF, MeOH, Acetonitrile

Emission: (in nm) 515

Molecular Formula: C₂₀H₂₁N

CAS Number: [79849-61-9]

Alternative Name: DMA-DPH

Unit Price (USD): 100 mg $152.79

Bulk Price/unit (when you buy 5 or more): $122.23

Description:
A useful fluorescent probe of lipid bilayer structure and dynamics. 1,6-Diphenyl-1,3,5-hexatriene (DPH) is a common fluorescent reagent used to monitor cell membrane interiors. Time-resolved fluorescence anisotropy and polarized fluorescence measurements of oriented samples have shown DPH to be mainly oriented parallel to the lipid bilayer axis, but it can also reside in the center of the lipid bilayer parallel to the surface. In order to improve the localization of DPH in the membrane, the polar derivatives DMA-DPH and TMA-DPH Product M1091 have been developed that contain a cationic trimethylammonium substituent which provides a membrane surface anchor.

Note:
Ex: 332nm

References:

• "Simultaneous double probing of the microenvironment in colloidal systems and molecular assemblies by DPH derivatives." Pistolis G, Malliaris A. Langmuir 13(6): 1457-1462 (1997).
• "Fluorescence monitoring of polarity change and gelation during epoxy cure." Lin KF, Wang FW. Polymer 35(4): 687-91 (1994).
• "1-[4-(Trimethylamino)phenyl]-6-phenylhexa-1,3,5-triene:synthesis, fluorescence properties, and use as a fluorescence probe of lipid bilayers." Prendergast FG, Haugland RP, Callahan PJ. Biochemistry 20: 7333-8 (1981).
• "Photophysical properties of DPH derivatives." Cundall RB, Johnson I, Jones MW, Thomas EW, Munro IH. Chemical Physics Letters 64(37): 39-42 (1979).