Pyrene 1-sulfonyl chloride

Product ID: M0524

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Useful amine reactive reagent for labeling proteins and peptides.

This reactive version of pyrenesulfonic acid can be used for labeling proteins and peptides as well as other groups in biological molecules or for attachment onto polymers or surfaces. The fluorescence emission is environment dependent.

Technical Data
SKU M0524
CAS Number 61494-52-8
Unit Size 25mg
Absorption 350nm
Emission Wavelength 380
Detection Method Fluorescence
Molecular Formula C₁₆H₉SO₂Cl
Molecular Weight 300.76
Soluble In Xylenes, anhydrous DMF. Prepare solution just prior to labeling.
Storage Conditions -20C, Desiccated, Protect From Light

References and Citations


  • "Cholesterol Dependent Recruitment of di22:6-PC by a G Protein-Coupled Receptor into Lateral Domains." A. Polozova, B.J. Litman., Biophys. J. 79:2632 (2000).
  • "Interaction of a novel fluorescent analog of interferon-gamma with transformed cells." Falach, A., Nathan, I., Baram, S., Porat, N., Dvilansky, A., Parola, A.H., Bioconjug. Chem, 8:459-465. (1997).
  • "Pyrene-labeled DNA probes for homogeneous detection of complementary DNA sequences: poly(C) model system." Yguerabide, J., Talavera, E., Alvarez, J.M., Afkir, M., Anal. Biochem. 241: 238-247 (1996).
  • "Photoinduced Electron Transfer for Pyrenesulfonamide Conjugates of Tryptophan-Containing Peptides." Jones, G., Bioorg. Med. Chem. Lett. 5:2385 (1996).
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