Reactive oxygen species (ROS) are a normal consequence of cellular activity, but under stress, levels can increase leading to oxidative damage to proteins, nucleic acid and lipids. Excessive ROS burden has been implicated in a variety of diseases, from cancer and stroke to atherosclerosis and neurodegenerative disorders like Alzheimer's disease. Marker Gene Technologies, Inc provides the most reliable and time tested reagents for following ROS changes in live cells as well as Rose Bengal for efficient production of ROS as a control.
This diacetate derivative of rose bengal exhibits greatly improved membrane permeability, allowing it to accumulate intracellularly where esterase activity releases the active rose bengal photosensitizer. Learn More
Reduced derivative of 2',7'-dichlorofluorescein is a cell permeable reagent for use in detection of peroxidase activity (oxidative metabolism, intracellular regulation of reactive oxygen species or oxidative burst) inside living cells. Learn More