Resorufin ethyl ether
Product ID: M1209
Microsomal dealkylase and Cytochrome P450 enzyme substrate. Releases the red fluorophore resorufin (Abs. 571 nm; Em. 585 nm) upon enzyme reaction. Routinely used to differentiate the various cytochrome P450 isoforms.
|Soluble In||DMSO, CH2Cl2|
|Storage Conditions||2-8C, Desiccated, Protect From Light|
- "Evaluation of alkoxyresorufins as fluorescent substrates for cytochrome P450 BM3 and site-directed mutants." (2005)Lussenburg BM, Babel LC, Vermeulen NP, Commandeur JN., Anal Biochem 341: 148-55.
- "Purification and biochemical characterization of two major cytochrome P-450 isoforms induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in chick embryo liver." (1994) Rifkind A.B., Kanetoshi A., Orlinick J., Capdevila J.H., Lee C. J., Biol. Chem. 269: 3387-3396.
- "Methoxyresorufin and benzyloxyresorufin: substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse." (1993) Nerurkar P.V., Park S.S., Thomas P.E., Nims R.W., Lubet R.A. Biochem. Pharmacol. 46: 933-943.
- "7-Ethoxyresorufin-O-deethylase activity in human hair roots: a potential marker for toxifying species of cytochrome P-450 isozymes." (1987) Merk H.F., Mukhtar H., Schutte B., Kaufmann I., Das M., Bickers D.R., Biochem. Biophys. Res. Commun. 148: 755-761
- "Multiple forms of cytochrome P-450 related to forms induced marginally by phenobarbital. Differences in structure and in the metabolism of alkoxyresorufins." (1986)Wolf C.R., Seilman S., Oesch F., Mayer R.T., Burke M.D., Biochem. J. 240: 27-33.
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