Rose bengal (4,5,6,7-Tetrachloro-2',4',5',7'-tetraiodofluorescein disodium salt)

Product ID: M1277

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Iodinated and chlorinated derivative of fluorescein. Since it does not easily cross live cell membranes, it has been used to stain dead or degenerated epithelial cells of the cornea and conjunctiva (including nuclei and cell walls) producing a red color.

Rose bengal has also been used as a generator of singlet oxygen in cell assays. The di-acetate derivative M0780 is a cell permeant version of this important biological stain.

Technical Data
SKU M1277
CAS Number 632-69-9
Unit Size 25mg
Absorption 561nm
Detection Method Fluorescence
Molecular Formula C₂₀H₂Cl₄I₄Na₂O₅
Molecular Weight 1017.64
Storage Conditions Room Temperature

References and Citations


    "Firefly Luciferin-activated Rose Bengal - In Vitro Photodynamic Therapy by Intracellular Chemiluminescence in Transgenic NIH 3T3 Cells" (2003) Theodossiou, T., Hothersall, J.S., Woods, E.A., Okkenhaug, K., Jacobson J., MacRobert A.J., Cancer Research 63: 1818-1821.
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